St John's Wort (Hypericum Perforatum)

The sunshine herb — mild-to-moderate depression, nerve pain, and anxiety from Europe's most clinically studied medicinal plant.

St John’s wort (Hypericum perforatum) is the most extensively researched herbal antidepressant in the world — with meta-analyses of over 30 clinical trials confirming its efficacy for mild-to-moderate depression, comparable to standard antidepressants and with significantly fewer side effects. Its active compounds — hypericin and hyperforin — modulate serotonin, dopamine, and noradrenaline reuptake simultaneously, while its anti-inflammatory flavonoids make it equally valuable for nerve pain, neuralgia, and anxiety. Named for its flowering at midsummer around St John’s Day, it has been used in European medicine for over 2,000 years.

Key Benefits
Mild-to-moderate depression · Anxiety & nervous tension · Nerve pain & neuralgia · Seasonal affective disorder (SAD) · Menopausal mood changes · Wound healing (topical)

How to Use
Steep 1–2 tsp dried St John’s wort in 250ml hot water for 5–10 mins. Drink 2–3 cups daily. Mild, slightly bitter, lightly floral flavour. Must be used consistently for 4–6 weeks for antidepressant effects — not a fast-acting herb. Pairs well with lemon balm or oat straw for anxiety blends.

When to Expect Results
Nerve pain relief: 1–2 weeks · Mood improvement: 4–6 weeks · Full antidepressant effect: 6–8 weeks of consistent daily use.

Who It's For
• Mild-to-moderate depression
• Seasonal affective disorder (SAD)
• Anxiety & nervous tension
• Nerve pain & neuralgia
• Menopausal mood & emotional support

Who Should Avoid
• On prescription antidepressants (SSRIs, MAOIs) — risk of serotonin syndrome; absolutely avoid
• On oral contraceptives — reduces effectiveness; use additional contraception
• On anticoagulants, HIV medication, cyclosporine, digoxin — significant CYP3A4 interactions
• Photosensitive skin — hypericin increases UV sensitivity
• Bipolar disorder — may trigger manic episodes
• Pregnant or nursing — consult GP

Storage
Store in an airtight, opaque container away from light to preserve hypericin. Best used within 12–18 months.

Organically grown · Third-party tested · Free from pesticides & contaminants.